diff --git a/src/keyboard.c b/src/keyboard.c
index 94337d2ba8c..67a7f129a51 100644
--- a/src/keyboard.c
+++ b/src/keyboard.c
@@ -8190,6 +8190,7 @@ process_pending_signals (void)
   handle_async_input ();
   do_pending_atimers ();
   do_async_work ();
+  process_pending_profiler_signals ();
 }
 
 /* Undo any number of BLOCK_INPUT calls down to level LEVEL,
diff --git a/src/lisp.h b/src/lisp.h
index f8bf92d665c..0d9ed9b7495 100644
--- a/src/lisp.h
+++ b/src/lisp.h
@@ -5974,6 +5974,7 @@ extern bool profiler_memory_running;
 extern void malloc_probe (size_t);
 extern void syms_of_profiler (void);
 extern void mark_profiler (void);
+extern void process_pending_profiler_signals (void);
 
 
 #ifdef DOS_NT
diff --git a/src/profiler.c b/src/profiler.c
index 66a0e37f92e..f22a0352e73 100644
--- a/src/profiler.c
+++ b/src/profiler.c
@@ -387,6 +387,9 @@ static enum profiler_cpu_running
 /* Hash-table log of CPU profiler.  */
 static struct profiler_log cpu;
 
+/* Number of unprocessed profiler signals. */
+static uintptr_t pending_profiler_signals;
+
 /* The current sampling interval in nanoseconds.  */
 static EMACS_INT current_sampling_interval;
 
@@ -402,7 +405,19 @@ handle_profiler_signal (int signal)
       count += overruns;
     }
 #endif
-  add_sample (&cpu, count);
+  pending_signals = true;
+  pending_profiler_signals += count;
+}
+
+void
+process_pending_profiler_signals (void)
+{
+  uintptr_t count = pending_profiler_signals;
+  if (count)
+    {
+      pending_profiler_signals = 0;
+      add_sample (&cpu, count);
+    }
 }
 
 static void