diff --git a/modules/lang/python/README.org b/modules/lang/python/README.org
index a0ef69f5b..ee3ede890 100644
--- a/modules/lang/python/README.org
+++ b/modules/lang/python/README.org
@@ -30,6 +30,8 @@ This module adds [[https://www.python.org/][Python]] support to Doom Emacs.
   support via [[https://python-poetry.org/][Poetry]].
 - +pyenv ::
   Enable Python virtual environment support via [[https://github.com/pyenv/pyenv][pyenv]]
+- +uv ::
+  Enable Python virtual environment support via [[https://github.com/astral-sh/uv][uv]]
 - +pyright ::
   Add support for the pyright LSP server (requires [[doom-module:+lsp]]).
 - +tree-sitter ::
@@ -44,6 +46,7 @@ This module adds [[https://www.python.org/][Python]] support to Doom Emacs.
 - [[doom-package:pip-requirements]]
 - [[doom-package:poetry]] if [[doom-module:+poetry]]
 - [[doom-package:pyenv]]
+- [[doom-package:uv-mode]] if [[doom-module:+uv]]
 - [[doom-package:pyimport]]
 - [[doom-package:py-isort]]
 - [[doom-package:python-pytest]]
@@ -74,6 +77,7 @@ This module has no hard requirements, but softly depends on:
 - [[doom-package:py-isort]] requires [[https://github.com/timothycrosley/isort][isort]] to be installed: ~pip install isort~
 - Python virtual environments install instructions at:
   - [[https://github.com/pyenv/pyenv][pyenv]]
+  - [[https://github.com/astral-sh/uv][uv]]
   - [[https://conda.io/en/latest/][Conda]]
   - [[https://python-poetry.org/][Poetry]]
   - [[https://pipenv.readthedocs.io/en/latest/][pipenv]]
diff --git a/modules/lang/python/autoload/uv.el b/modules/lang/python/autoload/uv.el
new file mode 100644
index 000000000..f532cacbc
--- /dev/null
+++ b/modules/lang/python/autoload/uv.el
@@ -0,0 +1,26 @@
+;;; lang/python/autoload/uv.el -*- lexical-binding: t; -*-
+;;;###if (modulep! +uv)
+
+;;;###autoload
+(defvar +uv--project nil)
+
+;;;###autoload
+(defun +python-uv-mode-set-auto-h ()
+  "Set uv-mode virtualenv from buffer-local variable."
+  (when (memq major-mode '(python-mode python-ts-mode))
+    (when (not (local-variable-p '+uv--project))
+      (make-local-variable '+uv--project)
+      (setq +uv--project (+python-uv-read-project-from-file)))
+    (if +uv--project
+        (uv-mode-set)
+      (uv-mode-unset))))
+
+;;;###autoload
+(defun +python-uv-read-project-from-file ()
+  "Read uv project root from .venv directory presence."
+  (when-let (root-path (projectile-locate-dominating-file default-directory ".venv"))
+    (let ((venv-path (expand-file-name ".venv" root-path)))
+      (if (file-directory-p venv-path)
+          root-path
+        (message "uv: .venv directory not found in `%s'." root-path)
+        nil))))
diff --git a/modules/lang/python/config.el b/modules/lang/python/config.el
index a0c0c0603..6a7b87426 100644
--- a/modules/lang/python/config.el
+++ b/modules/lang/python/config.el
@@ -216,6 +216,17 @@
   (add-hook 'doom-switch-buffer-hook #'+python-pyenv-mode-set-auto-h))
 
 
+(use-package! uv-mode
+  :when (modulep! +uv)
+  :after python
+  :config
+  (when (executable-find "uv")
+    (uv-mode +1))
+  (add-hook! '(python-mode-local-vars-hook python-ts-mode-local-vars-hook)
+             #'+python-uv-mode-set-auto-h)
+  (add-hook 'doom-switch-buffer-hook #'+python-uv-mode-set-auto-h))
+
+
 (use-package! conda
   :when (modulep! +conda)
   :after python
diff --git a/modules/lang/python/doctor.el b/modules/lang/python/doctor.el
index 47af20fcd..15fa9037c 100644
--- a/modules/lang/python/doctor.el
+++ b/modules/lang/python/doctor.el
@@ -26,6 +26,10 @@
     (unless (split-string (shell-command-to-string "pyenv versions --bare") "\n" t)
       (warn! "No versions of python are available via pyenv, did you forget to install one?"))))
 
+(when (modulep! +uv)
+  (unless (executable-find "uv")
+    (warn! "Couldn't find uv in your PATH")))
+
 (when (modulep! +conda)
   (unless (executable-find "conda")
     (warn! "Couldn't find conda in your PATH")))
diff --git a/modules/lang/python/packages.el b/modules/lang/python/packages.el
index ffb545812..1a41d4fff 100644
--- a/modules/lang/python/packages.el
+++ b/modules/lang/python/packages.el
@@ -19,6 +19,8 @@
 (package! pyvenv :pin "31ea715f2164dd611e7fc77b26390ef3ca93509b")
 (when (modulep! +pyenv)
   (package! pyenv-mode :pin "364bddb8f0c8ec022796210d8d3625a520e984b0"))
+(when (modulep! +uv)
+  (package! uv-mode :pin "7e7f9b90832210b65823c3d58e3255cd164394b7"))
 (when (modulep! +conda)
   (package! conda :pin "8a1a934a2de576d4158b1b12329be4f5be931a4a"))
 (when (modulep! +poetry)